Duragesic is often mixed with heroin and used recreationally, leading to overdose deaths. Duragesic is very potent, 50 to 100 times more potent than morphine and some Duragesic analogs may be as much as 10,000 times more potent than morphine. Due to its high potency, Duragesic abuse is responsible for many deaths.
Improper use and abuse of Duragesic can lead to dependence, tolerance, and addiction. Opiates can be habit-forming, causing not only physical, but also psychological dependence. Withdrawals may occur if the dose of the opiates is reduced or discontinued after long-term use.
Using opiates for an extended period can lead to tolerance, where the user needs to increase the dosage of their opiates to achieve the desired effect, whether the desired result is pain control or euphoria.
Once the patient develops a tolerance, it becomes even more difficult to stop using due to the withdrawals. Symptoms of withdrawals are an indication of physical dependence and addiction to the opiate Duragesic. Most patients describe withdrawals as the worst, most frightening experience one will ever encounter. One can only imagine the excruciating pain when the opiate user says that they’d rather die than go through the withdrawals. Duragesic physical dependence symptoms, such as withdrawals, lead to psychological dependence. That is when addiction takes over the mind and life of the Duragesic, opiate user.